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In addition, metformin treatment greatly reduced gestational diabetes mellitus (GDM) incidence (RR = 0.59, 95% CI 0.43–0.80) compared to placebo, which was attributed to improved β-cell responsiveness and reduced hepatic gluconeogenesis (Yu et al., 2024)

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GHK-Cu The increased expression of p63 of keratinocytes by both GHK-Cu and GHK suggests that GHK and its copper complex can promote the survival of basal stem cells in skin