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The MHRA has issued warnings about unlicensed injectable products, particularly those obtained online or administered in non-clinical settings, due to concerns about contamination, incorrect dosing, and lack of quality assurance
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The follow-up pivotal trial (METAOD006 / OPTIONS) enrolled a larger cohort and failed to replicate statistically significant weight loss, which led Metabolic Pharmaceuticals to halt the formal drug development program in 2007