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Potential Role of Sulfur-Containing Antioxidant Systems in Highly Oxidative Environments - PMC

[DOI] [PMC free article] [PubMed] [Google Scholar] 78

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Style:Poudre

Understanding Glutathione’s Role in Redox and Neurotransmission Systemic inflammation and oxidative stress have been observed alongside depressive disorders and certain anxiety-related presentations.7 In more resistant cases, elevations in markers such as IL-6, TNF-alpha, granulocytes, and increased microglial activity have been reported.8 Glutathione depletion has been noted across several of these conditions.8 Within neurologic contexts, glutathione is often discussed in relation to redox balance and oxidative stress, particularly in clinical presentations where inflammatory signaling or metabolic strain may be present.9 Rather than functioning as a stand-alone approach, glutathione is more commonly considered as one variable within complex mood and inflammatory profiles, especially when oxidative stress or low-grade inflammation appears to contribute to the overall clinical picture