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(2026) Key Takeaways: Melanotan 1 (MT1) is available for research purposes only and is not FDA-approved for human therapeutic use [1] Research protocols typically use subcutaneous doses ranging from 0.25 mg to 2.0 mg per injection [2] The peptide has a half-life of approximately 30-40 minutes, requiring multiple daily administrations in research settings Clinical trials have used loading doses of 0.16 mg/kg followed by maintenance doses of 0.08 mg/kg [1] Bioavailability via subcutaneous injection is approximately 85-90% compared to intravenous administration [2] All research applications require proper medical supervision and institutional oversight Storage requires refrigeration at 36-46°F (2-8°C) to maintain peptide stability How Melanotan 1 (MT1) Works in the Body Melanotan 1 (MT1) is a synthetic analog of α-melanocyte-stimulating hormone (α-MSH) with the amino acid sequence [Nle⁴-D-Phe⁷]-α-MSH