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Experimental work has associated Epithalon with modulation of genes such as: CD5 – linked to immune cell differentiation and adaptive immune responses IL-2 – involved in T-cell regulation and broader white blood cell signaling MMP2 – associated with extracellular matrix remodeling, collagen dynamics, and tissue repair Tram1 – related to protein processing and transport Arylalkylamine-N-acetyltransferase (AANAT) – a key enzyme in melatonin synthesis pCREB-related targets – transcription factors involved in circadian signaling and potentially anti-neoplastic pathways Telomerase-associated components – consistent with observations on telomere biology These gene-level interactions position Epithalon as a useful tool compound for studying how small peptides might influence transcriptional regulation in immune, connective, circadian, and genomic-maintenance pathways