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In a 2001 editorial published in the European Journal of Anesthesiology , Pollard & Pomfrett describe DSIP as “incredibly safe” because (a) no dose had ever killed an animal subject in clinical research and (b) “no significant side effects” — apart from transient headache, nausea, and vertigo in humans — have been reported.4 But the U.S

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Adverse effects emerging beyond 12 weeks of continuous use are not documented in published research of any duration in human subjects