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Weirath and Haskell-Luevano, reviewing melanocortin tool compounds in ACS Pharmacology and Translational Science in 2024, place MT-II alongside NDP-MSH and SHU9119 as reference ligands used to validate stably expressing melanocortin receptor cell lines and as core ligands in assessing cryo-EM structures of active and inactive receptor complexes

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For most people, 500–1,500 mg/day is a sensible range