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Similarly, in 3-nitropropionic acid (3-NPA)-induced oxidative ovarian damaged mice, PA significantly reduced the percentage of GC apoptosis and atretic follicles in ovarian tissues, increased the expression of antioxidant genes, and inhibited the expression of pro-apoptotic genes (Zhang JQ et al., 2015)

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Importantly, telomere length measurements in treated subjects showed significant elongation compared to controls