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29 In addition, aromatase inhibitors such as ezetimibe and anastrozole have shown efficacy as chemopreventive agents, although they have not yet been approved

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Where they are present together with the enzymes monodehydroascorbate reductase and dehydroascorbate (DHA) reductase (DHAR), the reducing actions of both NAD(P)H and GSH should mean that oxidized ascorbate is present at only trace concentrations under optimal conditions (Fig