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Indeed, when young mice are reared under PWSI conditions from postnatal day (P) 21 to P35, they exhibit reduced sociability and decreased myelin thickness in the mPFC, compared to normally group-housed controls, and these alterations persist even after subsequent re-exposure to a social environment [7]
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These data confirm our hypothesis and demonstrate that at least 2 different organisms are required for the anaerobic catabolism of l-carnitine to TMA