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Skin Brightening and Hyperpigmentation Reduction (Moderate-Strong Evidence — Human) Glutathione's skin-lightening effects have been documented in multiple clinical studies, making this one of the few cosmetic applications with published trial data

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Ammonia death is a distinct form of cell death driven by lysosomal and mitochondrial damage due to ammonia accumulation, characterized by lysosomal alkalization and mitochondrial swelling (15, 16)