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For the past three years, one of the biggest podcasters on the planet has told a story to millions of listeners across half a dozen shows: There was a little boy, and the boy’s family was happy, until one day, the boy’s family fell apart

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Thus it appears that Fas-mediated apoptosis is defective in human SLE, leads to loss of control of autoreactive B cells by CD4 + T cells and autoantibody production