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A fraction of Gln in astrocytes is transported into GABAergic neurons, where it is transformed into Glu (alternatively, Gln in astrocytes is converted into Glu and then transported into GABAergic neurons), which is ultimately converted into GABA by glutamate decarboxylase [4]

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To compare the predictions of our model to the patient records, we used their predictions of size and timing of dose for each of the 53 patients