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Induced ROS production in various cellular models has been shown to be suppressed by sulforaphane, including in neutrophiles [64], murine bone marrow-derived macrophages [72], PBMC [78], RAW264.7 cells [88,93], human lung epithelial cells (BEAS-2B) [136], N9 murine microglial cells [105], primary astroglial rat cultures or mouse cerebral cortices [106], primary cultures of cortical astrocytes from newborn pig brains [107], BV2 microglial cells [110], HUVECs [117], human brain endothelial cell [128], primary cultures of cerebral microvascular endothelial cells [107], mammary epithelial cells [130], airway epithelial [132,144], retinal pigment epithelial (ARPE-19) cells [133], Caco-2 cells [135], human lung epithelial cells (BEAS-2B) [136], primary mouse and tracheal and human bronchial epithelial cells [139], and human airway epithelial (NCI-H292) cells [144]
